Karin Roelofs is chair of the EPAN lab en Principle Investigator of the Affective Neuroscience PI group. She is Professor of Experimental Psychopathology at the Behavioural Science Institute and Donders Institute for Brain Cognition and Behaviour: Centre for Cognitive Neuroimaging. After obtaining her Masters’ Degrees in Neuro- and Clinical psychology, she graduated Cum Laude at the RU (2002). She was research fellow at the National Institutes of Health (NIH: Bethesda, USA) and worked as an Assistant and later Associate Professor at Leiden University (2001-2011). Thereafter she moved to the RU in Nijmegen were she became PI of the ‘Affective Neuroscience’ group. Her true passion is to study motivational behavior and hormone-brain interactions in healthy subjects and patients with stress-related disorders (anxiety and aggression). She is particularly interested in the neural control of automatic freeze and fight-or-flight tendencies and the way we shift between these active and passive action modes. She also studies the development of these neural control mechanisms in children and adolescents, as well as the predictive value of automatic defensive reactions for the development of stress-symptoms in high-risk professions such as the Police. She applies various neuroimaging techniques (fMRI, TMS, tDCS) combined with pharmacological interventions to study mechanisms of emotion control, as well as ways to manipulate and improve emotion control. Her research is funded by several European (ERC-starting and FP7) and Dutch (NWO: VIDI, ASPASIA and VICI) grants.